How Acupuncture Influences Cortisol Levels and the Brain’s Stress Response

A 2015 study explored how acupuncture affects the hypothalamic-pituitary-adrenal (HPA) axis, which regulates the body’s stress response. Key findings include:

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1. Acupuncture’s Targeted Effect: Specific acupoints, such as Shenshu (BL23) and Qimen (LR14), significantly reduce stress by regulating the secretion of corticotropin-releasing hormone (CRH) and promoting glucocorticoid receptor (GR) expression in the brain.

2. Long-Term Stress Reduction: By balancing CRH and cortisol levels, acupuncture influences both immediate and long-term stress responses, reducing chronic stress symptoms.

3. Behavioral Improvements: In animal models, acupuncture improved stress-related behaviors and enhanced resilience to external stressors.

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This research highlights acupuncture’s ability to modulate brain activity and hormone levels, offering a scientific foundation for its effectiveness in managing stress.

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